
张林,博士研究生,副教授,硕士生导师。E-mail: gmulinzhang@163.com
主要研究方向:绿色有机合成及不对称催化反应,药物合成及新药研发。
个人简介:2005.9-2014.7就读于四川大学化学学院,分别获得学士学位及博士学位。2015年5月起,任职于k1体育,承担本科生《无机化学》、《物理化学》等课程的教学任务。主要研究方向为绿色有机合成及不对称催化反应,药物合成及新药研发。目前以第一作者或通讯作者身份在J Catal, Org. Lett., ACS Sustainable Chem. Eng., Org. Chem. Front., J. Org. Chem.等学术期刊上发表研究论文20余篇,主持校级基金1项,省级科研项目3项。
代表性课题:
(1)贵州省科学技术基金,基于金鸡纳碱衍生的手性多齿配体修饰锰催化芳香酮不对称加氢反应研究,黔科合基础-ZK[2024]重点032,主持。
(2)贵州省科学技术基金,基于以二氧化碳为C1资源的多相催化合成杂环化合物研究,黔科合基础-ZK[2022]一般400,主持。
(3)贵州省科技厅联合基金,新型药物优势结构-杂化并嘧啶二酮的合成研究;黔科合LH字[2016]7359; 主持
代表性论文:
(1)Zhang L,Zhou X, Dai P, Gou W, Wang M, Tian Y, Xu Y,* Li C,* Synthesis of Enantiopure β‑Hydroxy-1,3-dioxolanes by Ir-Catalyzed Asymmetric Hydrogenation of α‑(1,3-Dioxolane)-ketones,Org. Lett.2025, 27, 8018−8022.(中科院一区)
(2) Meng X, Wang Y, Tian Y, Zhou Y, Zhou X, Tian W,Zhang L,* Xu Y,* Li C, * Cinchona-Alkaloid-Derived NNPP Ligands for Iridium-Catalyzed Asymmetric Hydrogenation of Unsymmetrical Benzophenones,Org. Lett.2025, 27, 10797−10801. (中科院一区)
(3) Dai P, Tian Y, Zhou X, Zhou Y, Tian W, Wang Y,Zhang L,* Xu Y,* Li C,*Mn-Catalyzed Asymmetric Transfer Hydrogenation of Ketones Improved by Cinchona Alkaloid-Derived NNS Ligands,J. Org. Chem. 2025, 90, 16993−17004. (中科院二区)
(4)Zhang L., Dai P., Meng X., Tian Y., Zhou X., Gou W., Wang Y., Li C.* Cinchona alkaloids-derived chiral ligands for Mn-catalyzed ATH of ketones: Improvement of enantioselectivity through π-π stacking-induced hydrogen bond,J. Catal. 2024, 439, 115758.(中科院一区)
(5) Zhang L.,* Ma N., Wang M., Gou W., Tian J., Xu Q., Zhao C., Li C.* (o-CF3PhO)3P as a simple coupling reagent for direct amidation via activation of amines,Org.Chem.Front., 2024, 11, 1796–1803.(中科院一区)
(6) Xu Q., Gou W., Dai P., Zhou X., Tian J., Meng X., Tian Y.,Zhang L.,* Li C.* Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of β-Keto Ester,J. Org. Chem., 2024, 89, 1446–1457.(中科院二区)
(7) Gou W., Dai P., Wang M., Wang Y., Ma N., Zhou X., Xu Y.,Zhang L.,* Li C.* Synthesis of Diverse Ureas from Amines and CO2at Atmospheric Pressure and Room Temperature,J. Org. Chem., 2024, 89, 12498−12507.(中科院二区)
(8)Zhang L., Chen Q., Li L., Ma N., Tian J., Sun H., Xu Q., Yang Y., Li C.* Synthesis of N-Unsubstituted and N3-Substituted Quinazoline-2,4(1H,3H)-diones fromo-Aminobenzamides and CO2at Atmospheric Pressure and Room Temperature,Org. Lett., 2023, 25, 2471–2475.(中科院一区)
(9) Tian J., Meng X., Sun H., Chen Q., Xu Q., Dai P., Li L.,Zhang L.,* Li C.* Cinchona-Alkaloid-Derived NN Ligands and Achiral Phosphines for Iridium-Catalyzed Asymmetric Hydrogenation of Heteroaromatic and α-Chloroheteroaryl Ketones,J. Org. Chem.,2023, 88, 9213–9224.(中科院二区)
(10) Chen Q., Sun H., Li L., Tian J., Xu Q., Ma N., Li L.,Zhang L.,* Li C.* The Ir-Catalyzed Asymmetric Hydrogenation of α-Halogenated Ketones Utilizing Cinchona-Alkaloid-Derived NNP Ligand to Produce (R)- and (S)-Halohydrins,J. Org. Chem.,2022, 87, 15986–15997.(中科院二区)
(11)Zhang L., Zhang L., Chen Q., Li L., Jiang J., Sun H., Zhao C., Yang Y., Li C.* Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones,Org. Lett., 2022, 24, 415–419.(中科院一区)
(12)Zhang L., Jiang J., Li L., Chen Q., Zhang L., Sun H., Li C.* Sustainable Synthesis of Amides from Carboxylic Acids and Equivalent Amounts of Amines Using a Reusable Brønsted Acidic Ionic Liquid as a Catalyst and a Solvent,ACS SustainableChem&Eng., 2022, 10, 8433–8442.(中科院一区)
(13)Li C., Wang M., Lu X., Zhang L., Jiang J.,Zhang L.* Reusable Brønsted Acidic Ionic Liquid Efficiently Catalyzed N-Formylation and N-Acylation of Amines,ACS SustainableChem&Eng.2020, 8, 4353–4361.(中科院一区)