晏英，理学博士，教授，博士生/硕士生导师，k1十年体育品牌青年骨干教师、优秀教师。贵州大学精细化工研究开发中心与中国科学院昆明植物研究所联合培养博士，入选贵州省第一批青年拔尖人才。近年主持国家自然科学基金（3项），贵州省自然科学基金及卫健委等项目10余项；先后以第一/通讯作者在Acta Pharmaceutica Sinica B,Journal of Agricultural and Food Chemistry,Chinese Journal of Chemistry,Pesticide Biochemistry and Physiology,Bioorganic Chemistry,Journal of Natural Products等期刊上发表学术论文28篇，并担任药学类专业期刊Journal of Agricultural and Food Chemistry,Phytochemistry,Fitoterapia,Chemistry & Biodiversity等审稿人；获授权发明专利6项；贵州省药学会药物化学专委会委员，Food & Medicine Homology青年编委；指导国家级老员工创新训练项目及第十八届“挑战杯”全国老员工课外学术科技竞赛获得省级A类一等奖；指导员工获得k1十年体育品牌优秀毕业论文。
研究方向：天然药物化学及活性天然产物结构优化
主要研究方向以植物中新颖结构、具有重要生理功能（抗病毒、抗肿瘤）的活性化学成分为研究目标，利用植物化学、化学合成、生物学等手段探讨其结构、活性以及作用机制（靶点）等，从中寻找药物先导和候选结构。
邮箱：crystal_yanying@126.com
通讯地址：贵州省贵安新区安康大道6号k1十年体育品牌
近年主持的代表性科研项目：
(1)国家自然科学基金青年科学基金项目，32500342，靶向IMPDH2抗三阴性乳腺癌prieurianin类型柠檬苦素的发现及作用机制研究，2026.01-2028.01，30万
(2)国家自然科学基金地区基金项目，82360687，黔产大戟属植物中假白榄烷型二萜类化合物激活自噬-溶酶体通路抗阿尔茨海默症活性研究，2024.01-2027.12，33万
(3)国家自然科学基金地区基金项目，31760089，两种植物中抗烟草花叶病毒活性成分的发现、构效关系及作用机制研究，2018.01-2021.12，38万
(4)贵州省自然科学基金一般项目，黔科合基础-ZK[2022]一般393，具有抗阿尔兹海默症活性的假白榄烷酯类化合物构效关系及作用机制研究，2017.09-2020.08，10万
(5)贵州省自然科学基金一般项目，黔科合基础[2017]1141，黔产药用植物复叶地黄连中TMV抑制剂的发现、构效关系、作用机制研究，2022.04-2025.03，10万
(6)贵州省青年拔尖人才，黔科协KJLYRC-[2026]142，2026/04-2031/03，50万
近年代表性研究论文：
1. Yu Zhu, Zhibi Zhang, Xueqin Dai, Wenjing Liu, Jian Sun, Jialing Liu, Yuxin Zhao, Wenlong Ren, Chenlong Pan, Zhongmei Zhou*,Ying Yan*, Longlong Zhang*, Ceshi Chen*. DHL-11, a novel prieurianin-type limonoid isolated fromMunronia henryi, targeting IMPDH2 to inhibit triple negative breast cancer.Acta Pharmaceutica Sinica B,2026,16 (1): 287-304.(中科院1区, TOP)
2.Ying Yan#,Ming-You Peng#,Ying Yang,Zhi-Bi Zhang,Long-Long Zhang,Lei Tang,Xu-Jie Qin*,Yuan-Yuan Cheng*,Ying-Tong Di*,Xiao-Jiang Hao. Highly Oxygenatedent-abietane Diterpenoid Lactones fromEuphorbia peplusand Their Anti-inflammatory Activity.Bioorganic Chemistry,2025, 154, 107989-108003.(中科院2区, TOP)
3. Lu Chen, Lulan Liu, Yingyao Li, Shipeng Guan, Lingling Fan, Xujie Qin, Yingtong Di, Lei Tang, Rongcan Luo*,Ying Yan*. Macrocyclic Diterpenoids fromEuphorbia peplusPossessing Activity Towards Autophagic Flux.International Journal of Molecular Sciences,2025, 26, 299-314.(中科院2区)
4. Qin-Dan Li, En-Ming Feng, Dan Wang, Hong Liang, Lu Chen, Lei Tang, Ying-Tong Di, Jie Zou, Xu-Jie Qin*,Ying Yan*. Chemical Constituents FromTrichilia connaroidesand Their Anti-Tobacco Mosaic Virus Properties.Chemistry & Biodiversity,2025, 22 (6): e202402850.
5.Ying Yan#,Pan Tang#,Siyu He,Xiangkai Kong,Rong-Hua Wang,Jing Shi,Tianyuan Zhang,Ying-tong Di*,Lei Tang*,Xiao-Jiang Hao*. Design, synthesis, anti-TMV activity, and structure-activity relationships ofseco-pregnane C21steroids and their derivatives.Journal of Agricultural and Food Chemistry,2024, 72, 21877−21891.(中科院1区, TOP,封面文章）
6.Ying Yan#,Dan Wang#,Fang-Jiao Zhou#,Yu-Han Zhao,Xu-Jie Qin,Yu Zhang*,Xiao Ding*,Xiao-Jiang Hao*. Structurally Diverse Limonoids fromTrichilia connaroidesand Their Antitumor Activities.Chinese Journal of Chemistry,2024, 42, 3567–3580.(中科院1区, TOP)
7. Ming-You Peng, Xiong Zhang, Qin-Dan Li, En-Ming Feng, Lu Chen, Hu-Cheng Yang, Bing Guo, Ying-Tong Di, Lei Tang, Rong-Can Luo*,Ying Yan*. Two new jatrophane diterpenoids fromEuphorbia helioscopiawith activity towards autophagic flux.Journal of Asian Natural Products research.2024, 26 (8): 900-909.
8.Ying Yan#,QiZhou#, Xiao-QianRan, Qing-YunLu, Cui-ShanZhang, Ming-YouPeng, LeiTang, Rong-CanLuo,* Ying-TongDi*,Xiao-JiangHao. Jatrophane diterpenoids fromEuphorbia peplusLinn. as activators of autophagy and inhibit Tau pathology.International Journal of Molecular Sciences,2023, 24 (2), 1088–1109.(中科院2区, TOP)
9.Ying Yan#, JieChen#, Ming-YouPeng, XiongZhang, En-MingFeng, Qin-DanLi, BingGuo, XiaoDing*,YuZhang*,LeiTang*. Sesquiterpenes fromCarpesium faberitriggered ROS-induced apoptosis and protective autophagy in hepatocellular carcinoma cells.Phytochemistry,2023, 214, 113805–113817.(中科院2区)
10.Ying Yan#,Xiao-QianRan#, DanWang, XiongZhang, Ming-YouPeng, Xiao-YanYan, LeiTang,HongLiang,Xu-JieQin,Ying-TongDi,Rong-CanLuo*,Xiao-JiangHao*,Yong-GangYao*. Munronin V with 7/7/6 tricarbocyclic framework fromMunronia henryiHarms inhibit Tau pathology via activating autophagy,Organic & Biomolecular Chemistry,2023, 21 (3), 514–519.
11. XiongZhang, Ming-YouPeng, En-MingFeng, Qing-DanLi, LuChen, Hu-ChengYang, BingGuo, HongLiang, Ying-TongDi*,LeiTang*,Ying Yan*. Terpenoids fromEuphorbia helioscopiaand their cytotoxic activities against H1975 cells.Chemistry & Biodiversity,2023, 20 (10), 202301061–202301069.
12. Jian-Yi Huang#, Ying Yang#, Hong Liang#, Xue-Xue Pu, Ying-Yao Li, Min Cai, Feng Guo, Lin Liu,Ming-Ming Cao,Ying Yan*, Yuanyuan Cheng*, Ying-Tong Di*, Xiao-Jiang Hao. Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant ofEuphorbia peplusL.Tetrahedron Letters,2023, 123, 154550–154556.
13.Ying Yan,DanWang, XiongZhang, Ming-YouPeng,Xiao-YanYan, Yu-ShangGuo, Meng-AoJia, JieZhou, LeiTang*,Xiao-JiangHao*. Anti-TMV activity and effects of three prieurianin-type limonoids fromMunronia henryi.Pesticide Biochemistry and Physiology,2022, 184, 105108–105117.(中科院1区, TOP)
14.Ying Yan#, Pan Tang#, Xiong Zhang, Dan Wang, Minyou Peng, Xiaoyan Yan, Zuquan Hu, Lei Tang *, Xiaojiang Hao*, Anti-TMV effects ofseco-pregnane C21 steroidal glycosides isolated from the roots ofCynanchum paniculatum.Fitoterapia,2022, 161,105225–105233.
15. Xuexue Pu#, Xiaoqian Ran#,Ying Yan#, Qingyun Lu, Jincun Li, Yingyao Li, Shipeng Guan, Mingming Cao, Jie Liu, Xiaojiang Hao, Rong Can Luo*, Yingtong Di*,Three new jatrophane diterpenoids fromEuphorbia peplusLinn. with activity towards autophagic flux.Phytochemistry Letters,2022, 50, 141–146.
近年代表性专利：
1.晏英，汤磊，王丹，张雄，彭明友.柠檬苦素类化合物、制备方法及其作抗烟草花叶病毒药物的应用，专利号：2021115459566。
2.晏英，罗荣灿，冉晓倩，姚永刚，郝小江，汤磊，王丹，彭明友，张雄.一种柠檬苦素类化合物Munronin V及其制备方法、衍生物和药物组合物及应用，专利号：202211535032.2。
3.晏英，王丹，丁骁，赵逾涵，周芳姣，汤磊. Trichilin型柠檬苦素类化合物及其提取分离方法和应用，专利号：2024112397735。
4.晏英，唐攀，汤磊，郝小江，邸迎彤.双裂孕烷型甾体衍生物及其制备方法和应用，专利号：2024111011639。
5.晏英，汤磊，张雄，陈策实，张龙龙，王燕娥，宁凤玲，刘嘉玲，柯燕坤.一种倍半萜类化合物及其制备方法和应用，专利号：2024115371099。
6.陈策实，张龙龙，晏英，朱玉，彭明友.柠檬苦素类化合物在制备预防和/或治疗癌症药物中的应用，专利号：ZL202410595834.5。
